Many Facets of Reproducibility


Figure 1

A pentagram showing five elements of scientific rigor - logic, experimental redundancy, error analysis, intellectual honesty, and probability and statistics.
Elements of rigorous science from Reproducibility for Everyone

Case Studies in Irreproducibility


Figure 1

heatmap of expression values
heatmap of expression values

Figure 2

Batch effect and complete confounding
Batch effect and complete confounding

Figure 3

boxplots of hippocampal volume
boxplots of hippocampal volume

Common Causes of Irreproducibility


Figure 1

no randomization with randomization still batch effects due to technician, time of day, weather, or any other variable not under study that influence the study nevertheless. Randomization balances out these other variables Batch effect and complete confounding


Figure 2